At first sight this appears to be yet another Tetris clone. Investigation reveals that the gameplay is considerably different - destroying the viruses is a tricky procedure that requires a strategy that's close to - but not the same as - Columns. As with all puzzle games Dr Mario has a problem with its long-term playability; it's great fun for a while but you'll be bored with it soon. However it's definitely one to be dug out of the cupboard on regular occasions in the same way as Tetris and Columns. Still it's a must-buy for all puzzle fans.